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. 2020 May 29;8:519. doi: 10.3389/fbioe.2020.00519

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Copyright © 2020 Yang, Shen, Lin, Cheng, Chen, Chen, Kumar, Lin, Lu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Organs-on-chips technology for tissue model development. (A) Organs-on-chips platform provides an in vitro model of various organs. Reproduced with permission from Zhang et al. (2017). (B) Comparison of experimental strategies for current in vitro, in vivo, and Organs-on-chips models. Adapted with permission from Nawroth et al. (2019). (C) A lung-on-a-chip microdevice reproduce human physiological respiratory movements. Reproduced with permission from Huh et al. (2010). (D) Construction of a lung-on-a-chip with tissue/organ-level physical microstructure and microenvironment. Reproduced with permission from Jain et al. (2018).