Figure 4.

Integrate multi-organ chip platforms to create complex interactions between human organs. (A) The design concept of the human body chip. One of the most promising in vitro system for replicating the systemic responses of human body. Reproduced with permission from Huh et al. (2011). (B) Four-organs-on-a-chip system employed intestine, liver, skin, and kidney tissue that proportionately simulated the physiological environment of the human body. Reproduced with permission from Maschmeyer et al. (2015).