Table 1.

Subject characteristics

Variable	Pre n = 30	EPeri n = 31	LPeri n = 30	EPost n = 26	LPost n = 27	P Value
Age, yr	38 ± 6	50 ± 3	50 ± 4	55 ± 3	62 ± 4	<0.001
Weight, kg	65.9 ± 9.8	71.3 ± 10.9	67.3 ± 11.9	71.8 ± 12.9	66.6 ± 14.0	0.19
Height, cm	165 ± 6	165 ± 6	166 ± 7	165 ± 6	161 ± 7	0.053
BMI, kg/m2	24.3 ± 3.8	26.1 ± 3.9	24.5 ± 3.9	26.6 ± 5.1	25.7 ± 5.1	0.21
WC, cm	80.6 ± 8.0	84.4 ± 10.4	82.1 ± 11.9	87.9 ± 13.9	83.5 ± 10.7	0.23
Total lean mass, kg	42.2 ± 3.6	44.3 ± 5.7	40.5 ± 5.1	42.3 ± 6.3	39.0 ± 5.5	<0.01
ALM, kg	17.8 ± 1.7	18.7 ± 2.7	16.8 ± 2.7	17.6 ± 3.1	16.0 ± 2.6	<0.01
Total fat mass, kg	21.6 ± 7.7	24.7 ± 6.9	24.8 ± 8.1	27.4 ± 8.0	25.7 ± 9.6	0.10
Trunk fat mass, kg	9.5 ± 4.0	12.1 ± 4.2	12.0 ± 4.6	13.2 ± 4.8	12.4 ± 4.9	<0.05
Estradiol, pg/mLa,b	79 [64, 110]	70 [37, 141]	34 [10, 94]	11 [10, 15]	10 [10, 14]	<0.001
Estrone, ng/dLa,b	61 [41, 70]	60 [34, 88]	43 [30, 69]	26 [24, 33]	26 [23, 37]	<0.001
FSH, μIU/mLb	6.5 ± 3.4	22.0 ± 30.0	64.1 ± 35.5	72.1 ± 26.1	84.1 ± 33.3	<0.001
Progesterone, ng/dLa,b	0.4 [0.2, 0.6]	0.5 [0.2, 0.8]	0.3 [0.2, 0.5]	0.3 [0.1, 0.4]	0.2 [0.1, 0.4]	<0.01
Testosterone, ng/dLa,b	24 [22, 33]	22 [17, 35]	20 [17, 25]	18 [17, 23]	17 [17, 35]	0.32
V̇o2peak, mL·kg−1·min−1c	31.2 ± 6.4	28.3 ± 4.8	27.5 ± 5.9	26.3 ± 3.6	24.7 ± 7.2	<0.001

Data are means ± standard deviation or

^amedian [interquartile range] for n subjects.

^bn = 118,

^cn = 139.

ALM, appendicular lean mass; BMI, body mass index; EPeri, early perimenopausal; EPost, early postmenopausal; FSH, follicle stimulating hormone; LPeri, late perimenopausal; LPost, late postmenopausal; Pre, premenopausal; V̇o_2peak, peak aerobic capacity; WC, waist circumference. Significant P values are in bold.