Table 2.

Parametric variation of the left ventricle-systemic circulation model parameters

Parameter	% Variation	%SV	%$V_{\text{LV}}^{\text{EDV}}$	%$P_{\text{LV}}^{\text{sys}}$	%${\overline{P}}_{\text{aor}}$	%ΔPaor	%PVA
Tmax	+25/−10	+4/−2	−1/0	+5/−2	+3/−2	+4/−1	+8/−4
b	+10	+19	+13	+18	+18	+19	+43
A	+50/−50	−3/+3	−2/+2	−3/+3	−3/+3	−3/+3	−6/+7
ef0	+83	−37	+10	−36	−34	−38	−61
Rper	+25/−10	−6/+3	−1/1	+10/−5	+14/−7	−5/+3	+5/−3
Vven0	+10/−25	−44/+30	−28/+23	−44/+40	−45/+44	−44/+32	−68/+69
Cart	+25/−25	−2/+1	−2/+2	−3/+3	−4/+3	−21/+34	−5/+3

LEGEND; . Parametric variation of the left ventricle (LV)-systemic circulation model parameters from their baseline values (Tables A1 and A2) and their effect on the percentage change in stroke volume (SV), end-diastolic volume ($V_{\text{LV}}^{\text{EDV}}$), systolic pressure ($P_{\text{LV}}^{\text{sys}}$), mean aortic pressure (${\overline{P}}_{\text{aor}}$), pulse pressure (ΔP_aor), and pressure volume loop area (PVA) from their baseline values of 57 mL, 112 mL, 135 mmHg, 112 mmHg, 30 mmHg, and 0.97 Pa·m³, respectively. A, elastic modulus; b, sarcomere relaxation rate; C_art, aortic compliance; e_f0, fiber orientation; LV, left ventricle; R_per, peripheral vascular resistance; T_max, isometric tension under maximal activation; V_ven0, resting venous volume