Table A1.

Passive and active material properties: inputs to the LV model

Parameter	Parameter	Value	Units	Reference
A – scaling parameter for LV’s passive stiffness	A	0.1	kPa	29
bff – stiffness in fiber direction	bff	29.9		29
bxx – shear stiffness normal to fiber direction	bxx	13.3		29
bfx – shear stiffness in fiber direction	bfx	26.6		29
ef0epi – fiber orientation in the epicardium	ef0epi	−60	deg	29
ef0endo – fiber orientation in the endocardium	ef0endo	+60	deg	29
Tmax – isometric tension under maximal activation	Tmax	200.0	kPa	30
Ca0 – peak intracellular calcium concentration	Ca0	4.35	μm	30
(Ca0)max – maximum peak intracellular calcium concentration	(Ca0)max	4.35	μm	30
B – shape of peak isometric tension-sarcomere length relation	B	4.75	μm−1	30
l0 – sarcomere length at which there is no active force	l0	1.58	μm	30
t0 – time to peak tension	t0	151	ms	30
m – slope of linear relaxation duration-sarcomere length relation	M	1,048	ms/μm	30
b – relaxation rate	b	−1,429	ms	30
lr – relaxed sarcomere length	lr	1.85	μm	30

LV, left ventricle.