Table 1.

CNS and PNS disease caused by SARS‐CoV2

CNS/PNS	Abnormality	Evidence level	Reference
CNS	Meningitis/encephalitis	Case reports	Mao et al, 1 Asadi‐Pooya and Simani, 2 and Duong et al 4
	Ischemic stroke	Case reports and RCS	Mao et al, 1 Yang et al, 6 Li et al, 7 Avula et al 8
	Seizures	Case reports and RCS	Mao et al, 1 Moriguchi et al, 3 and Lu et al 5
	Headache	Case reports and RCS	Mao et al 1
	Cerebral bleeding	RCS	Li et al 7
	Sinus venous thrombosis	RCS	Li et al 7
	Optic neuritis	Murine and Felline model	Seah et al 9
	Reduced alertness	RCS	Mao et al, 1  Wang et al, 10 Chen et al, 11 and Yin et al 12
PNS	Guillain‐Barre syndrome	Case report	Virani et al, 13 Sedaghat et al, 14 Toscano et al, 15 and Zhao et al 16
	MFS	Case report	Gutiérrez‐Ortiz et al 17
	Polyneuritis cranialis	Case report	Gutiérrez‐Ortiz et al 17
	Hyposmia/hypogeusia	Case reports and RCS	Mao et al 1 and Gutiérrez‐Ortiz et al 7
	Neuralgia	RCS	Mao et al 1
	Myalgia	Case report and RCS	Mao et al 1 and Fiorino et al 18

Abbreviations: CNS, central nervous system; MFS, Miller‐Fisher syndrome; PNS, peripheral nervous system; RCS, retrospective cohort studies; SARS‐CoV2, severe acute respiratory syndrome coronavirus‐2.