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. 2020 May 29;11:1124. doi: 10.3389/fmicb.2020.01124

TABLE 4.

Characteristics of patients with ATL during three different periods: 1984–1985, 1992–1993, and 2010–2011.

Year of diagnosis of patients 1984–1985 1992–1993 2010–2011
Total no. of patients 181 712 996
Evaluable no. of patients NA NA 922
M/F ratio 1.4 1.13 1.12
Subtype
Acute 102(56.4%) 489(69.4%) 456(49.5%)
Lymphoma 38(21.0%) 151(21.4%) 237(25.7%)
Chronic 25(13.8%) 36(5.1%) 131(14.2%)
Smoldering 16(8.8%) 29(4.1%) 98(10.6%)
Age at diagnosis, year
min, max (mean) 24,90(56.9) 25,87(58.9) 34,100(67/5)
Age at diagnosis category
<40 years NA 31 (4.4) 9 (1.0)
40–49 NA 133 (18.7) 42 (4.6)
50–59 NA 209 (29.4) 152 (16.5)
60–69 NA 191 (26.9) 307 (33.3)
70–79 NA 122 (17.2) 282 (30.6)
80< NA 24 (3.4) 130 (14.1)
Geographic area at diagnosis
Hokkaido/Tohoku 42(23.6%) 51(7.2%) 50(5.4%)
Kanto 9(5.1%) 35(4.9%) 59(6.4%)
Chubu-Hokuriku 1(0.6%) 91(12.8%) 55(6.0%)
Kinki 6(3.4%) 90(12.7%) 88(9.5%)
Chugoku-Shikoku 24(13.5%) 39(5.5%) 48(5.2%)
Kyushu-Okinawa 96(53.9%) 401(56.5%) 622(67.5%)

ATL = adult T-cell leukemia-lymphoma; IQR = interquartile range; SD = standard deviation; NR = not reported; NA = figure was available but information on the number was not; SD = standard deviation.