Table 1.

Clinical pathological parameters of HNSCC patients with or without CNV of m6A regulatory genes.

Variable		With CNV events	Without CNV events	Total	chi-square value	P
Age	< =60	223	13	236	4.205	0.0402
	>60	216	27	243
Gender	Male	329	22	351	6.462	0.0110
	Female	110	18	128
Clinical Stage	Stage I	14	5	19	9.623	0.0220
	Stage II	83	9	92
	Stage III	93	9	102
	Stage IV	249	17	266
Stage M	M0	424	39	463	1.63E-29	1
	M1	5	0	5
	MX	10	1	11
Stage N	N0	209	26	235	4.620	0.2018
	N1	74	6	80
	N2	141	8	149
	N3	7	0	7
	NX	8	0	8
Stage T	T1	28	5	33	4.369	0.2243
	T2	125	15	140
	T3	118	9	127
	T4	167	11	178
	TX	1	0	1

With or without CNV events: Cases have CNV or do not have CNV, confirmed by TCGA database. Ambiguous variables (Nx and Mx) were excluded from chi-square test. Bold values indicate P < 0.05 with significantly statistical difference.