Table 1.
Demographic and other information included in the current study.
Hospitalized n=18 |
Mild n=14 |
Pre-2020 HC n=103 | (−)rRT-PCR n=13 |
p | |
---|---|---|---|---|---|
Female (%) | 7 (39%) | 6 (43%) | 61 (59.2%) | 9 (69%) | 0.434 |
Age, median (range), yr | 61.5† (30–81) | 31.5† (26–81) | 62 (24–87) | 35.8 (29–63) | <0.0001 |
Race | <0.0001 | ||||
Asian | 2 (11%) | 0 | 2 (2%) | 1 (8%) | |
African American | 13 (72%)† | 0† | 15 (14%) | 3 (23%) | |
Non-Hispanic Caucasian | 3 (17%) | 12 (86%) | 82 (80%) | 8 (61%) | |
Hispanic | 0 | 1 (7%) | 0 | 1 (8%) | |
Other | 0 | 1 (7%) | 4 (4%) | 0 | |
Inpatient/outpatient* | 18/0 | 1/13 | - | 0/13 | <0.001 |
Days since symptom onset, median (range)* | 10.5 (4–24) | 18.5 (9–33) | - | 17 (2–43) | 0.057* |
Respiratory failure requiring intubation (%) | 14 (78%) | 0 | - | 0 | <0.001 |
Duration of disease, median (range), days | 10.5 (4–24) | 11 (4–23)† | - | 4.5 (1–30) | 0.126 |
Clinical symptoms* | |||||
Cough | 16 (89%) | 9 (64.3%) | - | 6 (46%) | 0.036 |
Fever/chills | 15 (83%) | 10 (71%) | - | 5 (38%) | 0.030 |
Shortness of breath | 13 (72%) | 6 (43%) | - | 3 (23%) | 0.022 |
Myalgia | 6 (33%) | 9 (64%) | - | 4 (31%) | 0.130 |
Headaches | 5 (28%) | 8 (57%) | - | 2 (15%) | 0.058 |
Sore throat | 2 (11%) | 6 (43%) | - | 5 (38%) | 0.096 |
Nasal congestion/rhinorrhea | 2 (11%) | 6 (43%) | - | 4 (31%) | 0.121 |
Diarrhea | 2 (11%) | 3 (21%) | - | 3 (23%) | 0.630 |
Anosmia | 0† | 6 (43%)† | - | 0 | <0.001 |
Fatigue | 1 (6%) | 2 (14%) | - | 2 (15%) | 0.623 |
Vomiting | 0 | 1 (7%) | - | 0 | 0.323 |
Never symptomatic* | 0 | 0 | - | 3 (23%) | 0.021 |
SARS-CoV-2 detected by rRT-PCR* | 16/16 | 9/9 | - | 0/13 | <0.001 |
Anti-S1-RBD IgG, median (range), OD | 2.04† (0.15–2.73) | 0.37† (0.08–2.09) | 0.12 (0.01–2.09) | 0.28 (0.02–0.91) | <0.001 |
Anti-S1 IgM, median (range) OD | 1.91 (0.31–2.95) | 2.12 (0.98–2.78) | 1.14 (0.33–2.53) | 2.07 (0.25–3.36) | <0.001 |
Anti-E IgM, median (range), OD | 2.23 (1.03–3.04) | 2.26 (1.28–3.67) | 1.52 (0.15–3.04) | 2.58 (0.46–3.10) | <0.001 |
Categorical and continuous variables which differed between groups are shown in bold.
Comparison between symptomatic, recovered, and (−)rRT-PCR groups only.
Different between hospitalized and mild cases at p<0.005.
n=8 for mild and n=10 for (−)rRT-PCR.