Table 3.

Probability for development and dissemination of PTM resistance in bacteria in sewage/manure and soil.

Source of resistance	Comment
In organic fertilizing products
Toxic metal resistant bacteria in fertilizing products	The probability of the simultaneous presence of AMR bacteria in sewage/manure is high (original articles reviewed).
Toxic metal resistance genes in fertilizing products and their mobility	The probability of the presence of toxic metal resistance genes in fertilizing products is high and transfer of such genes to bacteria in fertilizing products is possible.
Toxic metal residues and development of toxic metal resistant bacteria in fertilizing products	The probability of development of toxic metal resistance in susceptible bacteria due to toxic metals in fertilizing products is high.
In soil/environment
Spread of toxic metal resistant bacteria from fertilizing products to soil/environment	The probability of spread of toxic metal resistant bacteria from sewage/manure to the soil/environment is high.
Spread of toxic metal resistance genes from fertilizing products to environmental bacteria	The presence and transfer of toxic metal resistance genes from fertilizing products to bacteria in soil is possible.
Development of toxic metal resistance in bacteria in soil/environment due to toxic metals in fertilizing products	Development of resistance in susceptible bacteria in soil due to the presence of toxic metals in fertilizing products is possible.