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EUP reduces inflammatory cytokines in the blood. Rat serum was used to detect inflammation-related proteins (HMGB1, TNF-α, and IL-1β). Compared with the I/R group, EUP pretreatment significantly reduced the release of inflammatory factors, and EUP high-dose (EUPH) group had the greatest effect. The difference with statistically significance (★compared with the I/R group, P < 0.05. ▽compared with the EUPH group, P < 0.05).
