Table 1.
Characteristics and course of cholinergic urticaria in our 16 patients.
| Characteristics | Number (%) |
|---|---|
| Sex | |
| Male | 9 (56.3%) |
| Female | 7 (43.7%) |
| Mean age of onset (yr) | 28.0 ± 11.7 (15, 56) |
| Mean duration of cholinergic urticaria (yr) | 4.9 |
| Associated other urticaria | |
| Chronic spontaneous urticaria | 4 (25.0%) |
| Dermographism | 3 (18.8%) |
| Cold urticaria | 2 (12.5%) |
| Cold urticaria and dermographism | 1 (6.3%) |
| Angioedema | 1 (6.3%) |
| History of anaphylaxis | 0 |
| Personal history of atopy | 3 (18.8%) |
| Allergic rhinitis | 2 (12.5%) |
| Asthma | 1 (6.3%) |
| Allergic conjunctivitis | 0 |
| Atopic dermatitis | 0 |
| Treatment# | |
| sAH1 | |
| Hydroxyzine (2)∗ | 4 (25%) |
| nsAH1 | |
| Cetirizine (1-2)∗ | 7 (43.8%) |
| Loratadine (1-2)∗ | 6 (37.5%) |
| Fexofenadine (1-2)∗ | 12 (75%) |
| Levocetirizine (1)∗ | 1 (6.3%) |
| Desloratadine (1-2)∗ | 2 (12.5%) |
| Bilastine (2)∗ | 2 (12.5%) |
| AH2 | |
| Ranitidine (2)∗ | 4 (25%) |
| Remission (at the time of study) | |
| Yes | 6 (37.5%) |
| No | 10 (62.5%) |
| Mean disease duration (in 6 cases with remission, yr) | 4.3 ± 4.5 (0.3, 13.0) |
The data were shown as mean ± standard deviation (minimum, maximum) or number (%). Abbreviations: AH2: H2 receptor antagonist; CSU: chronic spontaneous urticaria; nsAH1: nonsedating H1 antihistamine; sAH1: sedating H1 antihistamine; yr: year. #One patient might have one or more medications. ∗The number of tablets per day.