Table 2.

The optimal cut-offs for prognostic factors according to ROC curves.

Variables	Threshold	Sensitivity	Specificity	AUC area (95% CI)	p value
Tumor size	4.75	0.744	0.385	0.735 (0.692-0.778)	<0.001
Leukocyte	6.17	0.459	0.404	0.502 (0.452-0.552)	0.941
Neutrophil	3.27	0.537	0.452	0.539 (0.489-0.589)	0.130
Hemoglobin	121.2	0.793	0.653	0.578 (0.528-0.627)	0.002
Fibrinogen	3.06	0.583	0.381	0.617 (0.569-0.665)	<0.001
Prealbumin	234.5	0.637	0.384	0.662 (0.616-0.709)	<0.001
Albumin	42.5	0.500	0.351	0.587 (0.538-0.637)	0.001
Globulin	29.9	0.194	0.148	0.505 (0.454-0.555)	0.855
SII	527	0.438	0.244	0.615 (0.566-0.664)	<0.001
NLR	2.2	0.426	0.256	0.593 (0.544-0.643)	<0.001
PNI	48.73	0.752	0.550	0.615 (0.566-0.663)	<0.001

ROC: receiver operating characteristic; AUC: area under curve; CI: confidence interval; SII: systemic immune-inflammation index; PNI: prognostic nutritional index; NLR: lymphocyte to neutrophil ratio.