Table 3.
The correlation between the SII and other clinicopathological parameters.
Variables | SII < 527 (cases) | SII ≥ 527 (cases) | p value |
---|---|---|---|
Total | |||
Sex | 0.062 | ||
Men | 230 | 102 | |
Women | 110 | 70 | |
Age (years) | 0.414 | ||
<55 | 159 | 87 | |
≥55 | 181 | 85 | |
SRCC | 0.384 | ||
mSRCC | 298 | 146 | |
pSRCC | 42 | 26 | |
Chemotherapy | 0.352 | ||
Yes | 167 | 77 | |
No | 173 | 95 | |
Tumor size (cm) | <0.001 | ||
<4.75 | 175 | 53 | |
≥4.75 | 165 | 119 | |
pT | <0.001 | ||
T1 | 74 | 10 | |
T2 | 45 | 19 | |
T3 | 39 | 23 | |
T4 | 182 | 120 | |
pN | <0.001 | ||
N0 | 127 | 39 | |
N1 | 60 | 26 | |
N2 | 67 | 33 | |
N3a | 60 | 42 | |
N3b | 26 | 32 | |
pTNM | <0.001 | ||
I+II | 173 | 47 | |
III | 167 | 125 | |
Tumor location | 0.079 | ||
Lower stomach | 227 | 101 | |
Middle stomach | 49 | 26 | |
Upper stomach | 25 | 10 | |
LM stomach | 29 | 24 | |
MU stomach | 2 | 5 | |
LMU stomach | 8 | 6 | |
Leukocyte | <0.001 | ||
<6.17 | 230 | 62 | |
≥6.17 | 110 | 110 | |
Neutrophil | <0.001 | ||
<3.27 | 231 | 29 | |
≥3.27 | 109 | 143 | |
Hemoglobin | <0.001 | ||
<121.2 | 60 | 80 | |
≥121.2 | 280 | 92 | |
Fibrinogen | <0.001 | ||
<3.06 | 204 | 64 | |
≥3.06 | 136 | 108 | |
Prealbumin | 0.005 | ||
<234.5 | 149 | 98 | |
≥234.5 | 191 | 74 | |
Albumin | 0.117 | ||
<42.5 | 187 | 82 | |
≥42.5 | 153 | 90 | |
Globulin | 0.292 | ||
<29.9 | 278 | 147 | |
≥29.9 | 62 | 25 | |
PNI | <0.001 | ||
<48.73 | 92 | 84 | |
≥48.73 | 248 | 88 | |
Total gastrectomy | 0.112 | ||
Yes | 68 | 45 | |
No | 272 | 127 | |
NLR | <0.001 | ||
<2.2 | 303 | 37 | |
≥2.2 | 37 | 135 |
SII: systemic immune-inflammation index; SRCC: signet-ring cell carcinoma; pSRCC: pure signet-ring cell cancer; mSRCC: mixed signet-ring cell cancer; LM: lower and middle; MU: middle and upper; LMU: lower, middle, and upper; PNI: prognostic nutritional index; NLR: lymphocyte to neutrophil ratio.