Table 1.
Age | Gender | IBD | Anti‐TNF | Duration of therapy (months) | Immunomodulator | Clinical Symptoms | ANA (baseline) (<7 IU/mL) | ANA (at diagnosis) (<7 IU/mL) | dsDNA (<7 IU/mL) | Anti‐histone | Anti‐Smith | Anti‐CCP | RF (<14k U/L) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
48 | M | CD | Infliximab | 21 | Nil | Polyarthritis | 0 | 30 | 38 | Pos | Neg | NA | NA |
69 | F | CD | Infliximab | 6 | Nil | Polyarthritis | 5 | 25 | 35 | Neg | Neg | 1 | <10 |
34 | F | CD | Infliximab | 9 | MMF | Rash | NA | 30 | NA | Neg | Neg | NA | NA |
57 | F | CD | Infliximab | 10 | Nil | Polyarthritis, | 6 | 15 | 10 | Neg | Neg | NA | <10 |
53 | F | UC | Infliximab | 3 | Nil | Polyarthritis, Rash | 2 | 10 | 0 | Pos | Neg | 1 | 11 |
51 | F | CD | Infliximab | 30 | AZA | Polyarthritis | NA | 30 | NA | Neg | Neg | NA | NA |
37 | F | CD | Infliximab | 9 | AZA | Polyarthritis | 2 | 30 | NA | NA | NA | NA | NA |
53 | F | CD | Infliximab | 10 | MTX | Polyarthritis | 0 | 30 | 22 | Neg | Neg | NA | NA |
39 | M | CD | Infliximab | 44 | Nil | Rash | 0 | 30 | 35 | Neg | Neg | 1 | <10 |
62 | F | CD | Infliximab | 30 | 6MP | Polyarthritis, | 7 | 30 | 6 | Neg | Neg | NA | NA |
36 | M | UC | Infliximab | 18 | Nil | Rash | NA | 25 | 6 | Neg | Neg | NA | NA |
49 | M | CD | Infliximab | 7 | Nil | Polyarthritis | 2 | 30 | 5 | NA | NA | NA | NA |
45 | F | UC | Infliximab | 33 | Nil | Rash | 7 | 30 | 7 | Neg | Neg | NA | NA |
21 | M | CD | Infliximab | 12 | Nil | Polyarthritis | 7 | 30 | 11 | Neg | Neg | NA | <10 |
42 | F | CD | Infliximab | 21 | Nil | Polyarthritis | 5 | 30 | 39 | Neg | Neg | 5 | <10 |
77 | F | CD | Infliximab | 3 | Nil | Polyarthritis | NA | 7 | 53 | NA | NA | NA | <10 |
51 | F | CD | Infliximab | 28 | Nil | Polyarthritis | 2 | 30 | 6 | Neg | Neg | 2 | <10 |
41 | F | CD | Adalimumab | 62 | Nil | Polyarthritis Polyarthritis | 0 | 30 | 52 | Neg | Neg | NA | NA |
Age–age at diagnosis of ATIL, Immunomodulator—concurrent at time of diagnosis.
AZA, Azathioprine; MMF, mycophenolate mofetil; MTX, methotrexate; 6MP, 6 mercaptopurine.