Table 1.
Characteristics of the study population according to thyroid hormone levels
| Variable | Euthyroidism (n = 70) | Subclinical hypothyroidism (n = 70) |
|---|---|---|
| Age (years) | 68.3 ± 7.3 | 69.1 ± 8.1 |
| Gender, female, n (%) | 34 (48.6) | 34 (48.6) |
| BMI (kg/m2) | 24.2 ± 3.7 | 23.6 ± 3.3 |
| ALT (IU/L) | 26.8 ± 26.1 | 45.5 ± 115.6 |
| AST (IU/L) | 27.4 ± 20.1 | 45.3 ± 88.9 |
| Gamma‐glutamyl transferase (IU/L) | 45.2 ± 45.7 | 104.9 ± 250.6 |
| Total cholesterol (mg/dL) | 204.7 ± 41.9 | 197.1 ± 42.2 |
| Triglyceride (mg/dL) | 132.9 ± 76.5 | 133.6 ± 95.7 |
| HDL‐cholesterol (mg/dL) | 58.0 ± 16.8 | 56.0 ± 18.6 |
| HbA1c (%) | 6.5 ± 1.7 | 6.1 ± 1.3 |
| Diabetes mellitus, n (%) | 36 (51.4) | 32 (45.7) |
| Hypertension, n (%) | 39 (55.7) | 39 (55.7) |
| FT4 (ng/dL) | 1.23 ± 0.16 | 1.16 ± 0.19 |
| TSH (μU/L) | 2.20 ± 1.05 | 6.02 ± 213** |
| NAFLD, n (%) | 10 (14.3) | 24 (34.3)** |
| ALT elevation, n (%) | 18 (25.7) | 27 (38.6) |
| AST elevation, n (%) | 16 (22.9) | 26 (37.1) |
**
P < 0.01 euthyroidism versus subclinical hypothyroidism.
Quantitative variables are presented as mean ± standard deviation or median (interquartile range).
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; FT4, free thyroxine; HDL, high‐density lipoprotein; NAFLD, non‐alcoholic fatty liver disease; TSH, thyroid‐stimulating hormone.