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. Author manuscript; available in PMC: 2020 Jun 5.
Published in final edited form as: Nat Med. 2019 Oct 7;25(10):1505–1511. doi: 10.1038/s41591-019-0594-0

Extended Data Fig. 9 |. μDystro, but not μutro, elicits a local cell mediated immune response after an intramuscular injection in the GSHPMD dogs.

Extended Data Fig. 9 |

Muscle biopsies were obtained four weeks post-intramuscular injection of μDystro and μUtro. a, Representative H&E stain of muscle biopsies. Right panel for each dog shows higher magnification of the corresponding boxed region. Scale bar, 50 μm. b, Immunofluorescence staining of muscle biopsies against Utro_N and Utro_C. Scale bar, 50 μm. c, Immunofluorescence staining of muscle biopsies against CD3 and CD8; the bottom merged panel offers a validation of both antibodies. All experiments were repeated independently at least two times with similar results.