Table 3.
Examples of 20-Year Absolute Risk Estimates (%) for Head and Neck Cancer in Women, by Risk Factor Profile, INHANCE Consortium, 1981–2010
|
Age and Alcohol
Consumption, drinks/day |
Cigarette Smoking | Education | Race/Ethnicity | Family History of HNC | Tumor Subsite | All HNCs | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Intensity, cigarettes/day | Duration, years | Oral Cavity | Oropharynx | Hypopharynx | Larynx | |||||
| Age 45 years | ||||||||||
| <1 | 0 | 0 | >HS | nHW | No | 0.06 | 0.01 | 0.00 | 0.01 | 0.08 |
| <1 | >20 | >20 | HS | nHW | No | 0.20 | 0.05 | 0.02 | 0.26 | 0.53 |
| ≥3 | >20 | >20 | >HS | nHW | Unknown | 1.01 | 0.42 | 0.11 | 0.13 | 1.68 |
| ≥3 | >20 | >20 | >HS | nHW | Yes | 0.98 | 0.42 | 1.40 | 0.52 | 3.30 |
| ≥3 | >20 | >20 | HS | Other | Unknown | 1.34 | 0.45 | 0.21 | 0.43 | 2.26 |
| ≥3 | >20 | >20 | HS | Other | Yes | 1.42 | 0.45 | 1.85 | 1.12 | 4.77 |
| Age 60 years | ||||||||||
| <1 | 0 | 0 | >HS | nHW | No | 0.10 | 0.02 | 0.00 | 0.01 | 0.13 |
| <1 | >20 | >20 | HS | nHW | No | 0.35 | 0.07 | 0.04 | 0.38 | 0.85 |
| ≥3 | >20 | >20 | >HS | nHW | Unknown | 1.73 | 0.59 | 0.21 | 0.51 | 3.06 |
| ≥3 | >20 | >20 | >HS | nHW | Yes | 1.71 | 0.59 | 2.71 | 0.76 | 5.71 |
| ≥3 | >20 | >20 | HS | Other | Unknown | 2.13 | 0.60 | 0.41 | 0.97 | 4.23 |
| ≥3 | >20 | >20 | HS | Other | Yes | 2.47 | 0.60 | 3.58 | 1.64 | 8.09 |
Abbreviations: HNC, head and neck cancer; HS, high school; INHANCE, International Head and Neck Cancer Epidemiology; nHW, non-Hispanic white.