Table 5.
Factors Associated With MDT Decision Making Using Univariate Logistic Regression
Variable | Comparison | P |
---|---|---|
Number of cerebral metastases | Single vs multiple | < .001 |
Age, y | < 65 vs ≥65 | < .001 |
KPS | < 70 vs ≥70 | < .001 |
Primary disease status | Controlled vs uncontrolled | < .001 |
Extracranial disease | Brain metastasis only vs brain and other metastases | < .001 |
Sentinel location | Lobes/cerebellum vs brainstem/basal ganglia/other | .05 |
Sentinel size, cm | ≤ 3 vs > 3 | .11 |
Time interval, y | < 2 vs > 2 | .93 |
Prior brain surgery | Yes vs no | .72 |
Histology of primary | SCLC vs TNBC | < .01 |
Preoperative neurological deficit | Yes (motor/speech/visual) vs no/missing | .09 |
Headache | Yes vs no | .10 |
Delay in MDT decision | Yes vs no | .28 |
MRI available | Yes vs no | > .001 |
Abbreviations: MDT, multidisciplinary team meeting; SCLC, small cell lung cancer; TNBC, triple-negative breast cancer.