Table 2.
Health state utility values and their plausibility ranges
Health state | Utility (base) | Plausibility range | Reference |
---|---|---|---|
Health states associated with prostate cancer | |||
Postoperative recovery phase after radical prostatectomy | 0.67 | 0.56–0.90a | Stewart et al. (25) |
Delivery of radiation therapy | 0.73 | 0.71–0.91a | Stewart et al. (25) |
Adverse effects of definitive treatment | |||
Erectile dysfunction | 0.89 | 0.86–1.00a | Stewart et al. (25) |
Urinary incontinence | 0.83 | 0.78–0.98a | Stewart et al. (25) |
Urinary incontinence and erectile dysfunction | 0.79 | 0.76–0.96a | Stewart et al. (25) |
Bowel dysfunction | 0.71 | 0.61–0.90a | Stewart et al. (25) |
Urinary incontinence and bowel dysfunction | 0.70 | 0.66–0.88a | Stewart et al. (25) |
Bowel dysfunction and erectile dysfunction | 0.57 | 0.41–0.76a | Stewart et al. (25) |
Urinary incontinence, erectile dysfunction, and bowel dysfunction | 0.45 | 0.17–0.78a | Stewart et al. (25) |
Biochemical recurrence | 0.67 | 0.56–0.84a | Stewart et al. (25) |
Symptomatic metastatic progression | 0.25 | 0.01–0.52a | Stewart et al. (25) |
Health states associated with kidney failure | |||
Conservative management | 0.900 | 0.700–1.000b | Hogan et al. (26) |
Management by transplantation | 0.775 | 0.675–0.875b | Hogan et al. (26) |
Management by hemodialysis | 0.525 | 0.450–0.600b | Hogan et al. (26) |
In the event a patient experienced two or more health states at the same time (e.g., delivery of radiation therapy and conservative kidney failure management), the current health state utility value was always determined by the state with the lowest value.
Interquartile range.
Range used in sensitivity analyses of the reference study.