Fig 2.

(A) Principal component analysis (PCA) and hierarchical clustering heatmap of pooled blood plasma miRNA expression profiles in intracerebral hemorrhage and ischemic stroke patients and in healthy controls (GSE43618) shows that differential expression of three miRNAs, similarly expressed in males (blue) and females (red), can distinguish the three groups from each other. (B) PCA and hierarchical clustering heatmap of renal medulla miRNA expression in hypertensive and normotensive patients (GSE28344) shows that one miRNA, miR-208b) is sufficient to discriminate between the two groups. (C) PCA and hierarchical clustering heatmap shows that the majority of sepsis-induced acute kidney injury (AKI) patients (GSE94717) can be distinguished from sepsis patients and from healthy subjects.