Table 1.
| Fig. Nbr. | Disease/Disorder | Gene Expression Omnibus accession number | p-value | q-value‡ | Nbr. of patients: healthy controls (P:C) | Sample | Discriminating miRNA variables (hsa-miR-?) |
|---|---|---|---|---|---|---|---|
| 1A | Acute myocardial infarction | GSE24548 | 0.0047 | 0.037 | 4P†:3C† | Platelets | 101, 106b, 140-5p, 142-3p, 142-5p, 15a*, 17*, 199a-5p, 19a, 200a, 20a*, 20b, 21, 21*, 219-5p, 223, 24–1*, 26b, 29b, 29c, 301a, 30a*, 30e, 32, 324-5p, 326, 33a, 33b, 340, 342-3p, 34a, 421, 454, 545, 548a-5p, 590-5p, 598 |
| 1B | Cardiac arrest | GSE34643 | 3.90E-04 | 0.07 | 5P†:5C† | Plasma | 574-5p, 1914*, miRBrightCorner30 |
| 1C | Premature coronary artery disease | GSE28858 | 8.00E-06 | 7.30E-04 | 12P:12C | Platelets | 548g, 1247, 1236, 526b, 551b*, 1278 |
| 2A | Intracerebral hemorrhage | GSE43618 | 0.0024 | n/d | 4P†:2C† | Plasma | 1228, 215, 516a-5p |
| 2B | High blood pressure | GSE28344 | 5.80E-04 | 0.29 | 5P:3C | Renal medulla | 208b |
| 2C | Sepsis-induced acute kidney injury | GSE94717 | 6.50E-04 | 0.02 | 12P:3C | Venous blood | 195-5p, 449c-5p, 4299, 3181, 3689f, 4704-5p, 21-3p, 188-3p, 1292-5p |
| 3A | Type 1 diabetes | GSE55099 | 0.002 | 0.2 | 12P:10C | Peripheral blood mononuclear cells | 1225-3p, 16, 26a,30a, 320a, 320b, 617 |
| 3B | Type 2 diabetes | GSE21321 | 1.48E-04 | 0.04 | 16P:10C | Whole blood | 144 (4 probes), 30d (4 probes) |
| 4A | Colon cancer | GSE16512 | 4.35E-05 | 8.20E-04 | 9P:14C | Serum | 197, 328, 885-5p |
| 4B | Prostate cancer | GSE16512 | 5.40E-06 | 4.20E-04 | 6P:14C | Serum | 197, 328, 636, 885-5p, 92a |
| 4C | Chronic lymphocytic leukemia (proliferating vs quiescent) | GSE53270 | 3.45E-04 | 4 Proliferating: 4 Quiescent | Whole blood | 150, 720 | |
| 4D | Diffuse large B-cell lymphoma(DLBCL) / Burkitt lymphoma(BL) | GSE22420 | 7.00E-25 | 1.58E-23 | 86DLBCL:64BL | Tumor cells | miRNA list available in PMID: 21701491 |
| 4E | Bladder cancer | GSE113486 | 1.00E-139 | 5.60E-139 | 392P:100C | Serum | miRNA list available in PMID: 30382619 |
| 5A | Chronic HIV patient | GSE38556 | 9.20E-04 | 0.1 | 8P:8C | Blood monocytes | 378. 315c |
| 5B | Chronic HIV patient / Long-term nonprogressor | GSE38556 | 5.30E-04 | 0.1 | 8HIV:8LTNP | Blood monocytes | 378* |
| 5C | Hemophilia A w/ and w/o inhibitors | GSE65581 | 9.60E-05 | n/d | 9P:5C | Whole blood | Multispecies miRNAs: ENSG00000252834_st gga-miR-107_st hp_mmu-mir-331_st mne-miR-107_25 |
| 5D | Viral meningitis / tuberculous meningitis | GSE131708 | 1.66E-04 | 0.06 | 8P:4C | Peripheral blood mononuclear cells | 1273g-3p, 150-5p, 4707-5p, 520f, 5584-5p |
| 6A | Multiple sclerosis (MS) | GSE17846 | 8.60E-08 | 1.60E-05 | 20P:21C (partial heatmap shown) | Whole blood | 145, 186, 20b |
| 6B | Amyotrophic lateral sclerosis (ALS) | GSE52670 | 2.80E-04 | 0.026 | 10P:10C | Spinal cord homogenate (post-mortem) | 1236, 1298, 378e, 520a-3p, 550b-3p, 595, 885-3p |
| 6C | MS vs ALS vs healthy control | GSE39643 | 4.80E-07 | 4.40E-06 | 16P:8C | Blood monocytes | 7a, 101, 103, 106b, 142-5p, 16, 19b, 24, 26a, 30b, 361-5p, 374a, 374b, 379, 518f, 93 |
| 7A | Alzheimer’s disease | GSE46579 | 1.35E-08 | 1.65E-06 | 48P:22C (partial heatmap shown) | Whole blood | 112, 144-5p, 151a-3p, 30d-5p |
| 7B | Mild cognitive impairment | GSE90828 | 4.55E-05 | 0.007 | 23P:30C (partial heatmap shown) | Plasma | 126*, 144, 151-3p, 30c |
| 7C | Old / young muscle | GSE23527 | 8.30E-04 | 0.22 | 17 old:19 young (partial heatmap shown) | Skeletal muscle | 144, 7–2* |
| 7D | Autism spectrum disorder (ASD) | GSE67979 | 0.005 | n/d | 5P:5C | Whole blood | 122-3p, 4270, 4430, 4697-5p, 5091 |
n/d = no data.
‡ False discovery rate.
† pooled samples.