Table 3. Univariate analysis of prognostic factors for disease-free survival.
| No. of patients | 3-year DFS rate | p | |
|---|---|---|---|
| Sex | |||
| Male | 149 | 74.5% | 0.523 |
| Female | 124 | 81.0% | |
| Age, years | |||
| < 75 | 168 | 81.2% | 0.005 |
| ≥ 75 | 105 | 72.8% | |
| Preoperative CEA | |||
| < 5 | 152 | 84.2% | 0.002 |
| ≥ 5 | 121 | 70.1% | |
| Postoperative CEA | |||
| < 5 | 221 | 81.1% | < 0.001 |
| ≥ 5 | 52 | 62.0% | |
| Tumor location | |||
| Right | 99 | 76.2% | 0.455 |
| Left | 101 | 74.0% | |
| Rectum | 73 | 83.7% | |
| Differentiation | |||
| Well | 10 | 67.5% | 0.710 |
| Moderately | 256 | 78.6% | |
| Poorly | 7 | 71.4% | |
| LVI | |||
| Yes | 163 | 71.9% | 0.023 |
| No | 110 | 85.9% | |
| PNI | |||
| Yes | 35 | 60.4% | 0.010 |
| No | 238 | 80.5% | |
| TNM Stage | |||
| I | 59 | 93.7% | < 0.001 |
| II | 110 | 84.4% | |
| III | 104 | 62.3% | |
| Smoking | |||
| Yes | 79 | 80.2% | 0.485 |
| No | 194 | 77.1% |
CEA, carcinoembryonic antigen; PNI, perineural invasion; LVI, lymphovascular invasion; TNM, tumor-node-metastasis