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. 2020 May 26;14(5):e0008237. doi: 10.1371/journal.pntd.0008237

Table 3. Frequency of Recognition and Area Under the Curve values for N. americanus L3 extract and recombinant SCP/TAPS proteins in the diagnosis of hookworm infection.

Antigen FoR (%)2 AUC3
N. americanus L3 extract 66 0.86
01818 43 0.68
01068 52 0.74
10402 41 0.64
01070 60 0.77
01068 + 01070 + 104021 82 0.83

1 the minimal antigen combination (01070, 01818 and 10402) which gives the highest frequency of recognition.

2 the recognition cutoff was defined as the average response of the HW -ve group + 1SD.

3 area under receiver-operating characteristic curves generated for each antigen and the antigen combination, which determines the positive predictive value of infection.