Table 1. Timeline of a female patient clinical evolution diagnosed with primary pulmonary sporotrichosis in Natal city, Rio Grande do Norte State, Northeast Brazil.

Period of time	Week 1	Week 2	Week 3	Week 4
Empirical antibacterial (LEV) and antifungal (FLU) therapy	X	X
Multiple bilateral pulmonary nodules (Chest X-ray)	X
Aspergillus sp. positive culture on sputum	X
Pulmonary nodular images and central necrosis (CT)	X
Antifungal therapy (AmB)		X
Corticosteroid treatment (PRS)		X
Antibacterial therapy (PTAZ)		X
ICU admission		X
Intravenous corticosteroid		X
Acute respiratory failure (mechanical ventilation)		X
Acute renal insufficiency and subsequently septic shock			X
Hemodialysis			X
Sporothrix brasiliensis BAL positive direct examination and culture			X
AmB to ICZ replacement			X
Death				X

^{LEV (Levofloxacin); FLU (Fluconazole); CT (Computed Tomography); AmB (Amphotericin B); PRS (Prednisone);}

^{PTAZ (Piperacilin + tazobactan); ICU (Intensive care Unit); ICZ (Itraconazole); BAL (Bronchoalveolar lavage)}