Table 6.

Results of 2-sample MR Analysis for Thyroid Cancer

	IVW		Egger			WM		PWM
Trait	OR (95% CI)	P Value	OR (95% CI)	P Value	Int P	OR (95% CI)	P Value	OR (95% CI)	P Value
BMI	0.84 (0.52-1.36)	0.48	0.70 (0.24-2.01)	0.51	0.71	1.04 (0.46-2.34)	0.93	1.04 (0.46-2.32)	0.93
WHR	0.98 (0.64-1.52)	0.94	1.46 (0.42-5.11)	0.55	0.51	1.04 (0.53-2.04)	0.91	1.07 (0.56-2.04)	0.84
WHR adjusted for BMI	0.98 (0.52-1.84)	0.94	0.51 (0.06-4.34)	0.54	0.54	1.27 (0.51-3.17)	0.61	1.32 (0.54-3.20)	0.54
Favorable adiposity	0.71 (0.15-3.29)	0.66	1.89 (0.02-162.9)	0.78	0.63	0.76 (0.09-6.53)	0.80	0.76 (0.09-6.65)	0.80
T2DM	0.99 (0.87-1.13)	0.91	0.92 (0.71-1.81)	0.50	0.43	0.94 (0.76-1.17)	0.58	0.94 (0.76-1.71)	0.59

Odds ratios, 95% CIs, and P values for the inverse variant weighted (IVW), Egger, weighted median (WM) and penalized weighted median (PWM) analyses are displayed. Int P represents the p-intercept of Egger analysis, which is a measure of horizontal pleiotropy.

BMI, body mass index; CI, confidence interval; WHR, waist-hip ratio.