. 2020 May 11;105(7):2430–2441. doi: 10.1210/clinem/dgaa256

Table 1.

Corticosteroids in Patients with and Residual Glucocorticoid Production

			Median (minimum-maximum)
Corticosteroid	N	LLoQ	GC+	GC–	P
18-oxo-cortisol (nmol/L)	192	0.046	0.00 (0.00-0.30)	0.00 (0.00-1.27)	<0.001^a
18-OH-cortisol (nmol/L)	192	0.046	0.26 (0.00-0.28)	0.00 (0.00-0.20)	<0.001^a
Aldosterone (pmol/L)^b	191	8.0	0 (0-220)	0 (0-25)	<0.001^a
Cortisone (nmol/L)	191	0.914	10.21 (1.63-46.88)	0.00 (0.00-4.16)	<0.001^a
Cortisol (nmol/L)^c	192	0.914	57.28 (5.48-507.04)	0.98 (0.00-27.18)	<0.001^a
DHEAS (nmol/L)	176	22.9	432.69 (25.07-2400.12)	0.00 (0.00-1459.51)	<0.001^a
21-deoxycortisol (nmol/L)	192	0.023	0.032 (0.00-14.50)	0.00 (0.00-1.05)	<0.001^a
Corticosterone (nmol/L)	191	0.114	3.50 (0.00-50.84)	0.00 (0.00-2.67)	<0.001^a
Allo-tetrahydrocortisol (nmol/L)	191	0.114	2.14 (0.00-21.54)	0.00 (0.00-1.56)	<0.001^a
11-deoxycortisol (nmol/L)	192	0.114	0.60 (0.12-2.87)	0.00 (0.00-0.21)	<0.001^a
Tetrahydrocortisol (nmol/L)	192	0.343	1.57 (0.00-17.06)	0.00 (0.00-2.84)	<0.001^a
Allo-tetrahydrocortisone (nmol/L)	192	0.343	0.00 (0.00-1.39)	0.00 (0.00–0.42)	<0.001^a
Tetrahydrocortisone (nmol/L)	192	0.114	0.95 (0.00–9.82)	0.00 (0.00-0.69)	<0.001^a
Androstendione (nmol/L)	175	0.023	0.92 (0.00-4.51)	0.440 (0.00-4.04)	<0.001^a
11-deoxycorticosterone (nmol/L)	191	0.023	0.12 (0.00-0.94)	0.00 (0.00-0.16)	<0.001^a
Testosterone (nmol/L)	176	0.023	7.74 (0.04-27.39)	0.34 (0.00-30.57)	<0.001^a
DHEA (nmol/L)	174	0.617	0.71 (0.00-4.33)	0.34 (0.00-1.97)	<0.001^a
17-hydroxy-progesterone (nmol/L)	192	0.114	2.90 (0.00-49.29)	0.73 (0.00-894.6)	<0.001^a
Epitestosterone (nmol/L)	176	0.023	0.06 (0.00-0.31)	0.00 (0.00-0.46)	0.008^a
Dihydrotestosterone (nmol/L)	176	0.206	0.57 (0.00-2.50)	0.00 (0.00-2.61)	0.020
Progesterone (nmol/L)	191	0.114	0.18 (0.00-81.35)	0.00 (0.00-48.27)	<0.001^a

GC+, residual glucocorticoid production; GC–, no residual glucocorticoid production;

Abbreviations: DHEA, dehydroepiandrosterone; DHEAS, dehydroepiandrosterone sulfate; GC, glucocorticoid; LLoQ, lower limit of quantification.

^aStatistically significant at 0.01 level.

^bTo convert serum aldosterone values (pmol/L) to ng/dL, divide by 27.7.

^cTo convert serum cortisol values (nmol/L) to μg/dL, divide by 27.6.