Table 3.
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-F, nM | 340 | 311 | 277 | 230 | 228 | 225 | 204 | 164 | 156 | 128 | 123 | 120 | 106 | 98 | 91 | 82 | 81 | 71 | 54 | 43 | 43 | 36 | 22 | 19 |
S-S, nM | 2.2 | 2.1 | 1.1 | 1.9 | 1.4 | 2.9 | 1.9 | 1.7 | 2.4 | 1.1 | 0.8 | 1.4 | 2.4 | 1.0 | 1.0 | 0.7 | 0.7 | 1.1 | 0.2 | 0.6 | 2.7 | 0.2 | 0.2 | 0.1 |
S-Aldo, pM | 217 | 69 | 135 | 121 | 56 | 25 | 14 | 15 | 86 | 104 | 39 | 39 | 15 | 92 | 53 | 28 | 29 | 51 | 66 | 31 | 24 | 38 | 10 | 33 |
S-CCN, nM | 51 | 25 | 39 | 38 | 7 | 13 | 13 | 17 | 15 | 9 | 18 | 8 | 6 | 4 | 9 | 9 | 3 | 4 | 4 | 4 | 2 | 2 | 2 | 2 |
Sex, M or F | F | M | F | F | M | F | M | F | F | F | M | F | F | F | F | F | M | F | F | M | F | M | M | F |
Age, years | 23 | 63 | 32 | 43 | 62 | 51 | 18 | 47 | 40 | 59 | 30 | 53 | 55 | 51 | 49 | 53 | 18 | 45 | 66 | 26 | 23 | 38 | 36 | 42 |
DD, years | 5 | 6 | 1 | 5 | 26 | 9 | 5 | 7 | 0.5 | 6 | 4 | 24 | 9 | 20 | 5 | 1 | 2 | 7 | 2 | 2 | 1 | 21 | 7 | 12 |
AC, yes or no | yes | yes | no | yes | yes | no | yes | yes | yes | no | yes | yes | no | no | yes | no | yes | no | yes | yes | no | no | yes | yes |
HCeq., mg | 20 | 25 | 20 | 20 | 20 | 10 | 28 | 30 | 30 | 20 | 25 | 20 | 15 | 10 | 17.5 | 20 | 30 | 20 | 20 | 40 | 30 | 30 | 30 | 25 |
BMI, kg/m 2 | 18.1 | 25.6 | 24.4 | 23.0 | 26.1 | 23.3 | 27.8 | 29 | 34.3 | 37.1 | 28.7 | 27.1 | 26.0 | 25.9 | 27.8 | 29.4 | 20.8 | 22 | 21.0 | 21.2 | 22.0 | 26.5 | 22.3 | 18.8 |
AddiQoL score | 66 | 89 | 72 | 102 | 94 | 95 | 90 | 105 | 73 | 117 | 86 | 80 | 93 | 95 | 80 | 96 | 102 | 101 | 93 | 99 | 83 | 91 | * | 91 |
P-ACTH, pmol/L | 63 | 32 | 26 | 70 | 34 | 68 | 39 | 210 | 62 | 237 | 82 | 67 | 120 | 134 | 88 | 259 | 224 | 225 | 31 | 278 | 125 | 43 | 278 | 175 |
PRC, mU/L | 500 | 187 | 146 | 302 | 48 | 308 | 76 | 325 | 122 | 124 | 179 | 22 | * | 465 | 61 | 337 | 77 | 107 | 22 | 152 | 350 | 214 | 81 | 915 |
Abbreviations: AAD, autoimmune Addison disease; AC, adrenal crisis ever; AddiQoL, AAD-specific questionnaire; BMI, body mass index; DD, disease duration; F, female; HCeq, hydrocortisone-equivalent dose; M, male; P-ACTH, plasma adrenocorticotropic hormone; PRC, plasma renin concentration; S-Aldo, serum aldosterone; S-CCN, serum corticosterone S-F, serum cortisol, S-S, serum 11-deoxycortisol.
* Not obtained.