. 2020 Apr 28;9(5):445–456. doi: 10.1530/EC-20-0129
This work is licensed under a Table 3.
Reported presenting features and severity of adrenal insufficiency patients under the care of the responding physicians.
| Patients’ characteristics | SSAa (n = 2885) | MENAa (n = 2902) | P-valueb | Total (%, 95% CI) | P-valuec |
|---|---|---|---|---|---|
| Presenting featuresd | |||||
| Gastrointestinal symptoms | 227 (82.2) | 52 (92.9) | 0.047 | 279 (84.0, 79.6–87.8) | |
| Nausea | 188 (79.7) | 46 (86.8) | 0.232 | 234 (81.0, 76.0–85.3) | Reference |
| Vomiting | 174 (73.7) | 43 (82.7) | 0.175 | 217 (75.3, 69.9–80.2) | 0.076 |
| Diarrhoea | 153 (66.2) | 43 (86.0) | 0.006 | 196 (69.7, 64.0–75.1) | <0.001 |
| Abdominal pain | 168 (71.2) | 47 (90.4) | 0.004 | 215 (74.6, 69.2–79.6) | 0.047 |
| Anorexia | 164 (71.0) | 42 (80.8) | 0.152 | 206 (72.8, 67.2–77.9) | 0.012 |
| Non-specific features | |||||
| Dizziness | 188 (79.7) | 49 (92.4) | 0.029 | 237 (82.0, 77.1–86.3) | Reference |
| Weight loss | 187 (77.3) | 47 (88.7) | 0.063 | 234 (79.3, 74.2–83.8) | 0.378 |
| Salt craving | 116 (50.7) | 30 (62.5) | 0.135 | 146 (52.7, 46.6–58.7) | <0.001 |
| Skin pigment | 154 (65.8) | 40 (75.5) | 0.175 | 194 (67.6, 61.8–73.0) | <0.001 |
| Backache | 115 (50.0) | 29 (56.9) | 0.375 | 144 (51.3, 45.2–57.2) | <0.001 |
| Adrenal crisis | 242 (16.4) | 134 (16.2) | 0.884 | 376 (16.3, 14.8–17.9) | |
| Features suggestive of adrenal crisis | |||||
| Hypoglycaemia | 162 (67.8) | 40 (76.9) | 0.195 | 202 (69.4, 63.8–74.6) | Reference |
| Loss of consciousness | 97 (42.5) | 21 (42.9) | 0.968 | 118 (42.6, 36.7–48.6) | <0.001 |
| Shock | 127 (54.3) | 29 (55.8) | 0.845 | 156 (54.6, 48.6–60.4) | <0.001 |
aResults are expressed as number (percentage); bP-value: comparison of clinical characteristics of patients between SSA and MENA; cP-value: comparison of all the patients in the entire cohort; dPercentages of common presenting features according to respondent doctors (n = 276 for SSA and 56 for MENA).