Table 1.
Clinical and epidemiological characteristics of the patients included
| Patient 1 | Patient 2 | Patient 3 | |
|---|---|---|---|
| Birth weight (g) | 3700 | 1135 | 3550 |
| Sex | M | M | M |
| Mode of delivery | Vaginal | Vaginal | Vaginal |
| Previous diagnosis | Severe hypoxic-ischemic encephalopathy, meconium aspiration and multiorganic failure | Prematurity (28 weeks), BPD | Hirschsprung’s disease |
| Parents tested | Yes. Mother positive | Yes. Mother positive | Yes. Parents negative |
| Time on MV since birth (d) | 6 | 0 | 0 |
| Time on NIV or nasal cannula since birth (d) | 16 | 70 | 0 |
| Respiratory support at diagnosis | MV | Room air | Room air |
| Fever | No | No | No |
| Minimum lymphocyte count (× 109/L) | 11.4 | 7.9 | 3.7 |
| Maximum CRP (mg/L) | 57 | < 1 | < 5 |
| Maximum PCT (ng/mL) | 0.82 | - | 0.1 |
| Maximum ferritin (ng/mL) | 491 | - | 1000 |
| Maximum D-dimer (ng/mL) | 5317 | - | 1891 |
d days, g grams, M male, BPD bronchopulmonary dysplasia, MV mechanical ventilation, NIV non-invasive ventilation, CRP C-reactive protein, mg milligrams, mL milliliter, ng nanogram, PCT procalcitonin