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. 2020 May 1;9:e53560. doi: 10.7554/eLife.53560

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© 2020, Corrigan et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 6. — The residual change in EE compared to site-appropriate controls for males of 2329 strains (A). Distribution of residual changes in EE for all KO strains with the numbers of KO strains reaching 1SD (green), 2SD (orange), or 3SD (red). Regression plots of EE vs mass (C) or residual EE vs mass for mice from mouse strains with known metabolic phenotypes (D). Lines showing ranges of standard deviations in EE are overlayed. Similar plots for IMPC strains with genes identified by obesity related GWAS and having phenotypes of more than 1 standard deviation (E, F). n = 23,309 males.

Figure 6—source data 1. IMPC dataset for 2329 knockout strains with residual and standard deviation values for EE.

elife-53560-fig6-data1.xlsx^{(804.3KB, xlsx)}