Figure 7. Select physiologic effects on EE.
Changes in EE for physiological challenges including age, voluntary wheel running exercise, β3 adrenergic agonism, warm and cold temperature compared to relative genetic changes as seen in Figure 6B (A). Regression plots for each intervention. Weeks of age (n = 5 per group) (B), weeks of exercise (n = 7) (C), a single dose of β3 adrenergic agonist CL316,243 in mice housed at 30°C (n = 10) (D), and temperature (n = 9) (E).