Table 1.
Baseline demographics, symptoms, endoscopy, and eosinophil counts (n = 883).
| Psychiatric diagnosis (n = 241) | No diagnosis or psychiatric medications (n = 583) | No diagnosis, on psychiatric medications (n = 45) | P value | |
|---|---|---|---|---|
| Demographics (N, %) | ||||
| Age (mean y ± SD)1 | 33.9 ± 18.3 | 23.5 ± 17.7 | 28.6 ± 18.6 | 0.06 |
| Symptom length (mean y ± SD)2 | 8.94 ± 8.9 | 6.74 ± 7.75 | 7.61 ± 7.63 | 0.01 |
| Male | 127 (53) | 433 (74) | 31 (69) | < 0. 001 |
| White | 211 (88) | 444 (77) | 30 (67) | < 0.001 |
| Atopic diagnosis | 107 (45) | 234 (42) | 18 (40) | 0.31 |
| Symptoms (N, %) | ||||
| Dysphagia | 187 (79) | 397 (69) | 33 (73) | 0.02 |
| Food impaction | 66 (28) | 179 (32) | 12 (27) | 0.23 |
| Heartburn | 109 (46) | 192 (34) | 10 (22) | 0.002 |
| Chest pain | 35 (15) | 47 (8) | 6 (13) | 0.03 |
| Abdominal pain | 56 (24) | 109 (19) | 9 (20) | 0.26 |
| Endoscopy findings (N, %) | ||||
| Normal | 21 (9) | 67 (12) | 12 (27) | 0.003 |
| Exudates | 90 (37) | 233 (40) | 13 (29) | 0.27 |
| Rings | 121 (50) | 258 (45) | 25 (56) | 0.16 |
| Edema | 80 (33) | 218 (38) | 14 (31) | 0.36 |
| Furrows | 149 (62) | 365 (63) | 23 (51) | 0.27 |
| Narrow | 39 (17) | 92 (16) | 5 (11) | 0.68 |
| Stricture | 57 (24) | 130 (22) | 11 (24) | 0.91 |
| Dilation | 66 (27) | 129 (22) | 11 (24) | 0.31 |
| Peak eosinophil count3 | ||||
| 63.8 ± 46.2 | 68.6 ± 44.8 | 59.6 ± 43.1 | 0.004 | |
1
Age at diagnosis;
2
Symptom length: Length of symptomatic period preceding diagnosis;
3
Max peak eosinophil count: eosinophils per high-power field ± SD standard deviation