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. 2020 Apr 21;34(6):651–659. doi: 10.1007/s40263-020-00730-8
Tapering with pharmaceutical gamma-hydroxybutyric acid (GHB) led to a milder withdrawal syndrome than tapering with benzodiazepines in patients with GHB use disorder during detoxification.
Patients with GHB use disorder had a one in five chance of developing delirium during detoxification when tapering with benzodiazepines, compared with 1 in 40 when tapering with pharmaceutical GHB.
There were no differences in GHB craving levels during detoxification between patients with GHB use disorder receiving pharmaceutical GHB tapering or benzodiazepine tapering.