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. 2020 Jun 5;11:2856. doi: 10.1038/s41467-020-16625-7

Fig. 8. B cell-deficiency attenuates IFN-β-treated TH17-EAE.

Fig. 8

TH17-EAE was induced in either C57BL/6 or µMT mice and treated with IFN-β or vehicle. a Clinical scores of vehicle-treated C57BL/6 (n = 10) and µMT (n = 10) mice with TH17-EAE. Data were pooled from two independent experiments. Mann–Whitney tests were performed to determine statistical significance (P < 0.05). b Number of CD4+ T cells that express GM-CSF and IL-17 in spinal cords of vehicle-treated mice (day 29). c Clinical scores of IFN-β-treated C57BL/6 (n = 10) and µMT (n = 11) mice with TH17-EAE. Data were pooled from two independent experiments. Mann–Whitney tests were performed to determine statistical significance (P < 0.05). d Number of CD4+ T cells that express GM-CSF and IL-17 in spinal cords of IFN-β-treated mice (day 29). Statistical analysis was performed using two-tailed Mann–Whitney tests. Error bars indicate the S.E.M. Results are compiled from two independent experiments. Source data are provided as a Source Data file.