Table 6.

Multivariable logistic predictive model for respiratory distress and mortality outcomes.

n (%)	ARDS			Mortality
	OR	CI 95%	p value	OR	CI 95%	p value
Age, >65 years	1.17	0.42–3.2	0.76	1.59	0.5–4.99	0.42
Sex, Female = 1	0.98	0.35–2.74	0.98	0.88	0.28–2.73	0.83
Smoking habit
Former smoker	0.81	0.27–2.45	0.72	0.89	0.25–3.11	0.86
Current smoker	2.4	0.48–11.8	0.28	2.48	0.5–12.54	0.27
Comorbidities
Hypertensiona	1.5	0.5–4.43	0.46	2	0.68–5.88	0.21
Diabetesa	2.4	0.63–9.44	0.19	1.15	0.34–3.9	0.81
CKDa	3.5	0.46–26.18	0.22	2.39	0.29–19.85	0.42
COPDa	0.79	0.18–3.34	0.75	0.35	0.05–2.23	0.26
Previous VTEDa	1.79	0.48–6.7	0.39	4.82	1.14–20.3	0.03
Chronic anaemiac	2.76	0.62–12.3	0.18	1.32
ACEI/ARBsIb	0.64	0.11–3.5	0.6	0.23	0.02–2.23	0.2
COPDd	1.69	0.33–8.62	0.52	1.43	0.25–8.33	0.68
Radiol infiltrates bilateral=1	21.4	4.2–108.55	<0.001	32.83	3.51–307	0.002
Neutropeniae
<1500	0.46	0.13–1.58	0.21	0.62	0.16–2.37	0.43
<500	10.36	0.93–114.52	0.056	16.54	1.43–190.9	0.025
Primary tumourf
Overall lung cancer	1.81	0.49–6.7	0.37	2.35	0.58–9.51	0.22
Colorectal cancer (lung=1)	1.65	0.1–16.97	0.81	2.33	0.17–30.94	0.52
Breast cancer (lung=1)	0.9	0.12–6.54	0.9	2.47	0.17–34.23	0.5
Genitourinary cancer (lung=1)	1.56	0.17–14.13	0.69	2.29	0.17–30.73	0.53
Other tumours (lung=1)	1.86	0.37–9.19	0.44	2.13	0.42–10.82	0.36
Metastatic diseaseg	1.11	0.23–5.38	0.88	1.88	0.19–18.19	0.58
Visceral metastatasish	0.7	0.21–2.25	0.54	1.32	0.38–4.55	0.44
Pulmonary involvementi	1.96	0.63–6.14	0.24	4.34	1.26–14.95	0.02
Cancer Treamentj
Chemotherapy alone	1.36	0.4-4-56	0.68	1.6	0.4–6.33	0.5
Immunotherapy + Chemo	0.97	0.14–6.45	0.95	1,96	0.29–13.18	0.49
Immnunotherapy alone	0.26	0.03–1.88	0.18	0.15	0.01–1.65	0.12

CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; VTED, venous thromboembolic disease; ACEi/ARBs, angiotensin converting enzyme inhibitor/angiotensin receptor blockers; ECOG, Eastern Cooperative Oncology Group; OR, odds ratio; CI, confidence interval.

^aAdjusted by age, sex, hypertension, diabetes, CKD, COPD, previous VTE, smoking habit.

^bAdjusted by age, sex, hypertension, diabetes, CKD, COPD, smoking habit.

^cAdjusted by age, sex, hypertension, diabetes, CKD, COPD, Previous VTE, smoking habit, oesophagogastric tumour.

^dAdjusted by age, sex, cardiopathy, previous VTED.

^eAdjusted by age, sex, hypertension, diabetes, CKD, COPD, Previous VTE, smoking habit.

^fAdjusted by age, sex, CT.

^gAdjusted by age, sex, COPD, previous VTE, metastasis, ECOG.

^hAdjusted by age, sex, previous VTE, pulmonary involvement.

ⁱAdjusted by age, sex, ECOG, metastasis, previous VTE.

^jAdjusted by age, sex, ECOG, metastasis, previous VTE, COPD.