Table 2.
Multidrug-resistant Gram-positive pathogens tested for sensitivity toward S. hominis S34-1 activity
| Type of species | Comment | Reference | Antibiogramsa |
|---|---|---|---|
|
CA-MRSAa (ST1) |
Strain MW2 (USA400) |
[17] | OXA, CFZ, PEN, CXM, FOX |
|
HA-MRSA (ST5) |
Strain HS72, pathogenic, isolated from abscess | [16] | OXA, LVX, CLI, CFZ, FOS, ERY, AMK, PEN, GEN, FOX |
| CA-MRSA (ST8) |
SF8300 (USA300) |
[18] | OXA, CFZ, ERY, PEN, CXM, FOX |
|
LA-MRSA (ST9) |
Pathogenic, isolated from bovine mastitis | [19] | OXA, LVX, CLI, CFZ, ERY, TGC, PEN, CXM, FOX |
|
CA-MRSA (ST30) |
Strain SF-1497 (USA1100) |
[18] | OXA, CFZ, PEN, CXM, FOX |
|
HA-MRSA (ST36) |
Strain SF 1208 (USA200) |
[18] | OXA, LVX, CLI, CFZ, ERY, SAM, PEN, CXM, FOX |
| CA-MRSA (ST59) | Strain RJ-2, pathogenic, isolated from skin infection | [15] | OXA, CLI, ERY, PEN, CXM, FOX |
|
CA-MRSA (ST72) |
Strain CN1, South Korea | [20] | OXA, CFZ, ERY, PEN, CXM, FOX |
|
CA-MRSA (ST80) |
Strain 07-02662, Germany | [21] | OXA, ERY, PEN, FOX |
|
HA-MRSA (ST239) |
Strain HS770, isolated from sputum | [16] | OXA, LVX, CLI, CFZ, ERY, AMK, SAM |
|
CA-MRSA (ST398) |
Pathogenic, isolated from blood | [22] | OXA, ERY, PEN, FOX |
| Staphylococcus capitis | Pathogenic, isolated from pleural fluid | This study | OXA, PEN, CIP, SXT, MXF, LVX |
| Staphylococcus epidermidis | Pathogenic, isolated from blood | This study | OXA, PEN, CIP, ERY, MXF, LVX |
| Staphylococcus hominis | Pathogenic, isolated from blood | This study | OXA, PEN, ERY |
| Streptococcus dysgalactiae | Pathogenic, isolated from sputum | This study | ERY |
| Streptococcus agalactiae | Pathogenic, isolated from urine | This study | CLI, LVX, CIP, MXF |
| Streptococcus salivarius | Pathogenic, isolated from blood | This study | PEN |
| Streptococcus constellatus | Pathogenic, isolated from blood | This study | PEN |
| Streptococcus pneumoniae | Pathogenic, isolated from sputum | This study | PEN, CLI, OXA, LVX, ERY, CLR |
| VRE (Enterococcus faecium) | Pathogenic, isolated from catheter | This study | VAN, PEN, CIP, LVX, ERY, LVX, TEC, TET, AMP, MXF, GEN, CLI, FOF |
| VRE (Enterococcus faecium) | Pathogenic, isolated from urine | This study | VAN, PEN, AMP, CIP, LVX, MXF, ERY, CLI |
| VRE (Enterococcus faecium) | Pathogenic, isolated from urine | This study | VAN, PEN, CIP, LVX, ERY, LVX, TEC, AMP, MXF, STR, CLI, FOF |
aAntibiograms were determined by disc diffusion on Mueller-Hinton agar according to Clinical and Laboratory Standards Institute guidelines
Abbreviations: OXA oxacillin, PEN penicillin, LVX levofloxacin, CFZ cephazolin, CXM cefuroxime, FOX cefoxitin, CLI cephalexin, FOS fosfomycin, ERY erythromycin, AMK amikacin, GEN gentamicin, TGC tigecycline, SAM sulbactam/ampicillin, SXT sulphamethoxazole/trimethoprim, MXF moxifloxacin, CIP ciprofloxacin, TET tetracycline, CLR clarithromycin, VAN vancomycin, TEC teicoplanin, STR streptomycin, FOF nitrofurantoin, LA live-associated, CA community-associated, HA hospital-associated