Table 2.
PPH outcomes by study group*
| Misoprostol (800mcg SL) (n = 40) |
Placebo (n = 39) |
RR 95% CI | P value | |
|---|---|---|---|---|
| Primary outcome | ||||
| Hb drop ≥2 g/dL a | 22 (56.4) | 20 (60.6) | 0.93 (0.61, 1.45) | 0.45 |
| Secondary outcomes | ||||
| Post-delivery Hb (g/dL), mean ± SD b | 10 ± 1.7 | 9.9 ± 1.7 | 0.94 | |
| Postpartum Hb ≤ 8 g/dL b | 7 (17.5) | 8 (21.1) | 0.83 (0.29, 2.33) | 0.78 |
| Pre to post-delivery Hb drop (g/dL), mean ± SD a | 2.4 ± 1.5 | 2.4 ± 1.8 | 0.99 | |
| Hb drop ≥3 g/dL a | 13 (33.3) | 12 (36.4) | 0.92 (0.45, 1.89) | 0.81 |
| Transferred to facility from home | 18 (45.0) | 15 (38.5) | 1.17 (0.66, 2.11) | 0.56 |
| Administered IV oxytocin at facility | 17 (42.5) | 14 (35.9) | 1.18 (0.64, 2.21) | 0.55 |
| Other interventions (Ns listed): | ||||
| Administered ergometrine | 2 | 6 | ||
| Manual removal of placenta | 2 | 1 | ||
| Suturing/tear repair | 1 | 1 | ||
| Hysterectomy/other surgery | 0 | 0 | ||
Abbreviations: Hb hemoglobin, SL sublingual, RR relative risk, CI confidence interval
* Data presented as n (%) unless otherwise stated
a Pre and post Hb measures available for n = 39 in the misoprostol arm and n = 33 in the placebo arm
b In one case (placebo) no post-delivery Hb was available for the one maternal death