Fig. 4.

MiR-518a-5p negatively regulated Fas in ovarian cancer cells. a The seed sequences of Fas WT/Mut and miR-518a-5p. b Relative expression level of Fas were detected by qRT-PCR in ovarian cancer tissues and paired adjacent normal tissues. c Bivariate correlation analysis of the relationship between miR-518a-5p and Fas expression level. d Dual-luciferase reporter assays were performed to detect the correlation between miR-518a-5p and Fas. e and f MiR-518a-5p negatively regulates Fas expression in SKOV3 and A2780 cells. Error bars represent mean ± standard deviation (SD). *p < 0.05, **p < 0.01, ***p < 0.001