Table 1.

Risk of bias for included RCTs

Authors, year	Selection bias, random sequence generation	Selection bias (allocation concealment)	Detection bias, blinding (outcome assessment)	Attrition bias, incomplete outcome data	Reporting bias, selective reporting	Performance bias, blinding (participants and personnel)
Debussche et al. 2018 [50]	Low	Low	Low	Low	Low	Low
Zhong et al. 2015 [51]	NCR	NCR	High	High	Low	NCR
Gagliardino et al. 2014 [52]	NCR	NCR	High	NCR	Low	High
Mash et al. 2014 [53]	Low	NCR	High	Low	Low	High

NCR no clear risk