. 2020 Jun 5;20:196. doi: 10.1186/s12877-020-01595-8

Table 1.

Descriptive characteristics of men and women at the 15-year follow-up visit and stratified by frailty groups. Values reported as means ±SD or median (IQR)

	All	Frail	Pre-frail	Robust	P-value
Women	N = 303	N = 47	N = 168	N = 88
Age (yr)	70 (65–75)	76 (70–84)	70 (65–75)	67 (63–72)	< 0.001
Weight (kg)	73.7 ± 15.0	73.0 ± 15.0	74.7 ± 15.0	72.4 ± 15.0	0.474
Height (m)	1.60 ± 0.06	1.57 ± 0.06	1.60 ± 0.06	1.61 ± 0.06	0.004
Body mass index (kg/m²)	29.0 ± 5.7	29.4 ± 5.5	29.4 ± 5.9	28.0 ± 5.3	0.141
Femoral neck bone mineral density (g/cm²)	0.835 ± 0.130	0.801 ± 0.136	0.844 ± 0.136	0.835 ± 0.108	0.127
FRAX scores^a
MOF-FRAX_BMD		12.0 (5.7–17)	6.1 (3.2–10)	4.6 (3.0–8.1)	< 0.001
MOF-FRAX_noBMD		14.0 (6.5–28)	7.5 (4.0–14.8)	5.9 (3.6–9.0)	< 0.001
Hip-FRAX_BMD		3.8 (1.3–6.1)	1.45 (0.4–3.6)	1.0 (0.4–2.6)	< 0.001
Hip-FRAX_noBMD		5.8 (2.0–13)	2.6 (1.0–6.6)	1.8 (0.9–3.6)	< 0.001
Men	N = 282	N = 41	N = 147	N = 94
Age (yr)	71 (66–78)	78 (73–74)	71 (66–79)	68 (64–71)	< 0.001
Weight (kg)	82.7 ± 12.4	88.1 ± 13.2	82.0 ± 12.7	81.4 ± 11.09	0.011
Height (m)	1.72 ± 0.08	1.71 ± 0.08	1.72 ± 0.06	1.73 ± 0.10	0.510
Body mass index (kg/m²)	28.0 ± 4.3	30.1 ± 4.1	27.5 ± 3.6	27.5 ± 5.1	0.002
Femoral neck Bone mineral density (g/cm²)	0.935 ± 0.137	0.961 ± 0.153	0.921 ± 0.123	0.947 ± 0.149	0.158
FRAX scores
MOF-FRAX_BMD		4.2 (3.0–5.5)	3.5 (2.3–1.2)	2.7 (1.7–4.3)	< 0.001
MOF-FRAX_noBMD		6.2 (4.0–7.3)	4.0 (2.5–7.1)	3.0 (1.1–4.7)	< 0.001
Hip-FRAX_BMD		1.6 (0.8–2.3)	1.0 (0.5–2.2)	0.7 (0.3–1.6)	< 0.001
Hip-FRAX_noBMD		3.1 (1.6–3.8)	1.6 (0.7–3.7)	0.9 (0.4–2.0)	< 0.001

^aFracture risk assessment (FRAX), Major Osteoporotic Fractures (MOF) FRAX score with Bone mineral density (BMD)(MOF-FRAX_BMD), MOF-FRAX score without BMD (MOF-FRAX_noBMD), hip FRAX with BMD (hip-FRAX_BMD),)_, hip FRAX score without BMD (hip-FRAX_noBMD)