Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 5;20:171. doi: 10.1186/s12876-020-01288-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 2 — CD44v8–10 showed up-regulation in CRC at the expense of other CD44 splicing variants. a Diagram of the method to calculate PSI_junc5’, which represents the usage of a junction among all junctions sharing the same 5’ splice site. The boxes are exons. Thick bars connected by a dotted line represent a read cover two exons (junction read). a, b and c are read counts for the three junctions. b Similar to (a) except that diagram of PSI_junc3’ was shown, which represents the usage of a junction among all junctions sharing the same 3’ splice site. c CD44 gene structure (bottom) and read coverage (Sashimi Plot) for exon 5 to exon 16 regions. d Boxplot of PSI of CD44 junc_5’ E5-v8 (top row), junc_5’ E5-E16 (middle row) and junc_3’ v10-E16 (bottom row) in CRC18P (left column) and CRC10P (right column) datasets. Dots in the boxplot represent individual patient data. P-value is based on Wilcoxon rank-sum test