Fig. 3.

Mean node age and mean evolutionary rate estimates and their 95% HPD intervals for time-scaled phylogenies of the five different subsampled datasets (A–E), which were each analyzed in BEAST in three different ways: including DRC66 and its tip age (estimates represented by squares), including DRC66 but with its sampling date unknown and to be estimated (estimates represented by circles), and excluding the DRC66 sequence (estimates represented by triangles). See also SI Appendix, Table S1. (A) Age estimates of the root of the tree (open characters) and of the node representing the common ancestor of conventional subtype C (filled characters) for each of the three BEAST analyses. (B) Age estimates of the clade that encompasses both conventional subtype C and DRC66 (squares and circles with crosses) for the two BEAST analyses that included DRC66 and the estimated sample ages of DRC66 for those analyses in which this was left to be estimated (stars). (C) Estimates of the evolutionary rate along the terminal branch leading to DRC66 in BEAST analyses that included DRC66’s sampling date (stars) and mean evolutionary rates across entire phylogenies for each of the three BEAST analyses.