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. 2019 Jul 23;28(20):3339–3354. doi: 10.1093/hmg/ddz177

Figure 8.

Figure 8

Structure of the I445M-hE3 variant (PDB ID: 6I4T). (A) (2mFo-DFc) composite omit map (2.0σ) confirms the substitution in I445M-hE3. (B) H+/H2O channel and relevant polar side chains are shown (as for Fig. 6B) in I445M-hE3 (dark/light teal; FAD′: raspberry) and hE3 (beige/grey; FAD′: beige). In I445M-hE3, both Glu332 and Arg460 were modeled with single conformations.

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