miRNA-25 |
2.65 ↓ |
0.0210 |
Dicer regulation; Oncogene (PTEN) suppression; calcium accumulation in mitochondria; apoptosis; mitochondrial function; suppression of colon cancer cells proliferation; oncogene (SMAD 7/ TGF β) suppression |
— |
|
[41] |
miRNA-30c |
2.25 ↓ |
0.0235 |
Protein repair; cell proliferation; stem cell recruitment; multi-drug resistant; stress (NFkB) response; oncogene (BCL9) suppression |
Lung |
Modulated by Metformin in mouse lung |
[33, 34] |
Breast |
Ovary |
miRNA-92b |
2.16 ↓ |
0.0495 |
Dicer regulation; cell proliferation; apoptosis; Oncogene (PTEN) suppression |
Lung |
|
[43] |
miRNA-133b |
2.01 ↓ |
0.0269 |
Muscle response to physical activity; associated with heart failure; oncogene (EGF) suppression; cell proliferation; cancer invasion |
Skeletal muscle |
|
Heart |
miRNA-204 |
4.08 ↓ |
0.0170 |
Epithelial mesenchymal transition; apoptosis; cell proliferation; oncogene (VHL) suppression; removal of cancer cells by mitochondrial driver autophagy; regulation of autophagy induced by ischemia-reperfusion in heart (rat) |
— |
|
[40, 44] |
miRNA-206 |
2.21 ↑ |
0.0297 |
Muscle response to physical activity; associated with breast cancer prognosis and patients survival; oncogene (Wnt) suppression; cell proliferation; cardiac regeneration; inhibition of cancer invasion; metalloprotease (TIMP-3) inhibition |
Skeletal muscle |
|
[33, 36] |
Breast |
miRNA-450a |
2.22 ↓ |
0.0048 |
— |
Heart |
Decreased in heart of diabetic mice |
[8] |
miRNA-492 |
2.56 ↓ |
0.0110 |
Angiogenesis |
Blood vessels (endothelium) |
|
[46] |
miRNA-513b |
2.11 ↓ |
0.0378 |
Inflammation; apoptosis |
Lymphoma |
|
|
miRNA-516b |
2.56 ↓ |
0.0053 |
Metastasis suppressor |
Melanoma |
|
[12] |
miRNA-519e |
2.22 ↓ |
0.0078 |
Cell proliferation; Oncogene (HuR) suppression |
— |
|
[45] |
miRNA-711 |
3.14 ↓ |
0.0277 |
Inhibition of heart fibrosis after heart infarction |
— |
Modulated by Pioglitazone in rat heart |
[39] |
miRNA-765 |
2.13 ↓ |
0.0396 |
Oncogenic protein (HMGA1) suppression |
Prostate |
|
[47] |
miRNA-877 |
2.06 ↓ |
0.0163 |
— |
Hepatocellular carcinoma |
Pioglitazone (2,10 up regulation in mouse lung) |
|