Table 2.
Demographic data, the patient characteristics and ECMO data of 8 multicentre studies with H1N1 outbreak (2009–2010)
| Study group | Data collection/population | ECMO pts./total H1N1 pts. | Age of ECMO pts. (years) | PaO2/FIO2a (mmHg) | MV durationa (days) | ECMO duration (days) | Discharged aliveb, n (%) |
|---|---|---|---|---|---|---|---|
| ANZ ECMO Influenza Investigator [40] | Retrospective/15 ICUs | 68/194 | 34.4 (26.6–43.1) | 56 (48–63) | NA | 10 (7–15) | 32 (47.1%) |
| UK ERP with SwiFT study [41] | Prospective/4 centres | 75c | 36.5 ± 11.4 | 54.9 ± 14.3 | 4.4 ± 3.7 | NA | 57 (76%) |
| Italian ECMO network [42] | Prospective/14 ICUs | 60/153 | 39 (32–46) | 63.3 (56–79) | 2 (1–5) | 10 (7–17) | 41 (68.3%) |
| Australian ERP [43] | Retrospective | 38 | NA | 63 | NA | NA | 33 (86.8%) |
| Japanese Society [44] | Retrospective/12 ICUs | 14 | 54 | 50 (40–55) | 5 (0.8–8.5) | 8.5 (4.0–10.8) | 5 (35.73%) |
| REVA Research Network in France [45] | Prospective/114 ICUs | 123 | 42 ± 13 | 63 ± 21 | 2 (1–5) | 9.8 | 79 (64.2%) |
| Germany ARDS network [46] | Retrospective/40 centres | 61/116 | 42 (39–45)d | 87 (74–101)d | NA | NA | 28 (45.9%) |
| Italian ECMO network [47] | Prospective/14 centres | 60 | 39.7 ± 12 | NA | NA | NA | 41 (68.3%) |
Mean ± SD or median (interquartile range)
ANZ Australia and New-Zealand, ECMO extracorporeal membrane oxygenation, ERP ECMO Retrieval Program, ICU intensive care unit, MV mechanical ventilation, NA not applicable, pts. patients, SwiFT Swine Flu Triage
aData before ECMO support
bDischarged alive of patients who underwent ECMO support
cMatched pairs among total 80 ECMO referred patients
dMean values (95% confidence interval)