Figure 2.

Relation between read-depth and mutation call status. We examined the read-depth for 1,267 loci in 16 cells. Note that these loci were selected with at least two mutations in the 16 cells. We first divided these 1,267 loci into four groups based on the MAFs of these loci in bulk tumor sample. Then within each MAF group, we examined the read-depths for the cases where somatic mutations are called (Yes) versus the cases where somatic mutations are not called (No). The vertical line indicate read-depth cutoff 20. This figure appears in color in the electronic version of this article, and any mention of color refers to that version.