Table 2.

Association between multi-morbidity score and disability domains in Boston RISE participants

Disability Outcome measures	Beta Coefficient	Odds Ratio	95%CI	Standardized Beta Coefficient	95%CI	P value
Body function/structures
Leg Strength (N/kg)	−0.15		−0.26, −0.03	−0.06	−0.10, −0.01	0.01
Leg Velocity (m/s)	−0.01		−0.02, 0.002	−0.04	−0.09, 0.01	0.10
Leg Power (Nm/s)	−9.78		−16.18, −3.38	−0.06	−0.10, −0.02	0.003
Trunk Extensor Endurance (s)	−3.76		−6.61, −0.92	−0.06	−0.11, −0.02	0.01
Ankle ROM Impairment		1.01	0.91, 1.13	-	-	0.81
Foot Sensory loss		1.00	0.89, 1.12	-	-	0.99
Activity
400-minute walk time	0.08		−0.02, 0.18	0.04	−0.01, 0.09	0.10
SPPB score	−0.17		−0.27, 0.07	−0.07	−0.12, −0.03	0.001
Gait Speed	−0.02		−0.03, 0.01	−0.08	−0.12, - 0.04	0.0002
LLFDI -BLF	−0.99		−1.52, −0.46	−0.08	−0.13, −0.04	0.0003
LLFDI - ALF	−1.41		−2.03, −0.79	−0.10	−0.14, −0.05	<0.0001
Participation
LLFDI - PL	−1.08		−1.63, −0.53	−0.09	−0.14, −0.04	0.0002
LLFDI - PF	−0.39		−0.64, −0.14	−0.07	−0.11, −0.03	0.002

Multivariable linear and logistic regression models with disability measures as the dependent variables and the multi-morbidity score as the main predictor variable, with each model adjusted for age, race, gender, Body Mass Index, Physical activity score, pain score, and Mini Mental State Examination Score. The estimate represents the number of units of change in outcome associated with an increase of 1 point in the multi-morbidity score except for Range of Motion impairment and sensory loss where the estimates are the Odds Ratios. Abbreviations: CI -Confidence Interval, ROM-Range of Movement, SPPB – Short Physical Performance Battery, LLFDI-Late Life Function and Disability Instrument, BLF – Basic Leg Function, ALF – Advanced Leg Function, PL- Participation Limitation, PF -Participation frequency