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. 2020 Jun 7;135:251–259. doi: 10.1016/j.ejca.2020.05.028

Table 3.

Prognostic factors for survival.

Characteristics N Deaths
Univariate analysis
Multivariate analysis
N (%) HR (95%CI) p HR (95%CI) p
All patients 302 (100%) 30 (10%)
Age>60 179 22 (12,2%) 2,01 (1,21–2,81) 0,083
Male gender 144 21 (14,5%) 2,66 (1,90–3,42) 0,01 2,75 (1,91–3,59) 0,019
KPS<60 114 20 (17,5%) 9,01 (8,07–9,95) <0,001 4,87 (3,87–5,87) 0,002
Relapsing cancer 177 27 (15,2%) 6,81 (5,63–7,99) <0,001 3,05 [1,83-4,27] 0,073
Fever & respiratory symptoms 130 25 (19,2%) 6,90 (5,94–7,86) <0,001 5,09 (4,11–6,07) 0,001
Lung cancer 42 8 (19,0%) 2,38 [1,58-3,18] 0,03
Covid-19 suspect CT Scan 59 9 (15,2%) 2,55 (1,63–3,47) 0,051
SARS-COV2 RT-PCR+ 55 8 (14,5%) 1,92 (1,12–2,72) 0,1
CRP>50 133 22 (16,5%) 3,13 (2,23–4,03) 0,009
Ly < 700/μL 91 18 (19,7%) 4,84 (4,02–5,66) <0,001 3,05 (2,19–3,91) 0,05
SARS-COV2 RT-PCR+ pts 55 (100%) 8 (14%)
Age>60 40 8 (20%) 33,9(27,4–40,5) 0,026
Male gender 26 7 (26,9%) 8,19 (6,09–10,3) 0,014
KPS<60 17 6 (35,2%) 7,7 (6,09–9,31) 0,005
Fever & respiratory symptoms 36 8 (22,2%) 36,9 (30,5–43,3) 0,017
Lung cancer 7 3 (42,9%) 4,69 [3,24-6,14] 0,16 ND
Covid-19 suspect CT scan 27 7 (25,9%) 0,89 (−0,64–2,42) 0,072
Relapsing cancer 31 7 (22,5%) 5,29 (3,19–7,39) 0,061
CRP >50 18 6 (66,6%) 6,87 (4,75–8,99) 0,039
Ly < 700/μL 13 3 (23,1%) 8,98 [6,71-11,3] 0,037
SARS-COV2 RT-PCR neg. pts 247 22 (8%)
Age>60 139 14 (10.1%) 1,4 (0,54–2,26) 0,43
Male gender 118 14 (11.9%) 1,97 (1,11–2,83) 0,11
KPS<60 97 19 (19.6%) 10,6 (9,38–11,82) <0,001 6,64 (5,41–7,87) 0,003
Relapsing cancer 146 20 (13.7%) 7,5 (6,05–8,95) <0,001 4,26 (2,79–5,73) 0,053
Fever & respiratory symptoms 94 17 (18.1%) 5,78 (4,78–6,78) <0,001 4,9 (3,90–5,90) 0,002
Covid-19 suspect CT scan 32 2 (6.2%) 0,89 (−0,64–2,42) 0,87
CRP>50 115 16 (13.9%) 2,67 (1,67–3,67) 0,05
Ly < 700/μL 78 15 (19.2%) 4,39 [3,49-5,29] 0,001 2,16 (1,24–3,08) 0,09

HR, hazards ratio; CI, confidence interval; CT, computed tomography; KPS, Karnofsky performance status.