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. 2020 Jun 6;20:877. doi: 10.1186/s12889-020-09015-7

Table 3.

Pooled prevalence of Toxoplasma gondii infections in relation to age, gender and characteristics of study population

Variables No. of Studies Pooled Estimates (95% CI) Heterogeneity Meta-regression
Sample size Cases Prev. (%) Q-value I2 (%) Q-p P- value OR (95% CI)
Age*
 Children 7 1365 551 18.52 6.02, 44.63 342.16 98.25 < 0.001 0.451 0.37 (−0.59, 1.33)
 Adults 7 2790 1224 36.93 29.04, 45.59 106.08 94.34 < 0.001 Reference
Total 14 4155 1775 29.55 21.19, 39.55 448.80 97.10 < 0.001
Gender < 0.001
 Male 15 2391 1052 31.85 21.79, 43.94 353.07 96.04 < 0.001 0.835 −0.07 (−0.70, 0.57)
 Female 22 4263 1667 30.61 22.95, 39.51 620.71 96.62 < 0.001 Reference
Total 37 6654 2719 31.23 25.15, 38.02 981.86 96.33 < 0.001
Target Population
 Pregnant women 20 6560 2990 40.25 33.19, 47.73 600.05 96.83 < 0.001 0.034 0.35 (−0.21, 0.91)
 Healthy individuals 11 1372 313 23.32 17.25, 30.75 70.24 85.76 < 0.001 −0.49 (−1.16, 0.18)
 HIV patients 16 4061 1163 31.68 20.53, 45.41 767.23 98.05 < 0.001 Reference
Total 47 11,993 4466 32.94 27.61, 38.74 1614.29 97.15 < 0.001

*(P = 0.022); CI Confidence interval; HIV Human immunodeficiency virus; I2 Inverse variance index; MOD Method of diagnosis; OR Odds Ratio; Prev. Prevalence; Q-p Cochran’s p-value