Table 3.
Variables | No. of Studies | Pooled Estimates | (95% CI) | Heterogeneity | Meta-regression | |||||
---|---|---|---|---|---|---|---|---|---|---|
Sample size | Cases | Prev. (%) | Q-value | I2 (%) | Q-p | P- value | OR (95% CI) | |||
Age* | ||||||||||
Children | 7 | 1365 | 551 | 18.52 | 6.02, 44.63 | 342.16 | 98.25 | < 0.001 | 0.451 | 0.37 (−0.59, 1.33) |
Adults | 7 | 2790 | 1224 | 36.93 | 29.04, 45.59 | 106.08 | 94.34 | < 0.001 | Reference | |
Total | 14 | 4155 | 1775 | 29.55 | 21.19, 39.55 | 448.80 | 97.10 | < 0.001 | ||
Gender | < 0.001 | |||||||||
Male | 15 | 2391 | 1052 | 31.85 | 21.79, 43.94 | 353.07 | 96.04 | < 0.001 | 0.835 | −0.07 (−0.70, 0.57) |
Female | 22 | 4263 | 1667 | 30.61 | 22.95, 39.51 | 620.71 | 96.62 | < 0.001 | Reference | |
Total | 37 | 6654 | 2719 | 31.23 | 25.15, 38.02 | 981.86 | 96.33 | < 0.001 | ||
Target Population | ||||||||||
Pregnant women | 20 | 6560 | 2990 | 40.25 | 33.19, 47.73 | 600.05 | 96.83 | < 0.001 | 0.034 | 0.35 (−0.21, 0.91) |
Healthy individuals | 11 | 1372 | 313 | 23.32 | 17.25, 30.75 | 70.24 | 85.76 | < 0.001 | −0.49 (−1.16, 0.18) | |
HIV patients | 16 | 4061 | 1163 | 31.68 | 20.53, 45.41 | 767.23 | 98.05 | < 0.001 | Reference | |
Total | 47 | 11,993 | 4466 | 32.94 | 27.61, 38.74 | 1614.29 | 97.15 | < 0.001 |
*(P = 0.022); CI Confidence interval; HIV Human immunodeficiency virus; I2 Inverse variance index; MOD Method of diagnosis; OR Odds Ratio; Prev. Prevalence; Q-p Cochran’s p-value